*** H2O2 induced LOH ~ ARLS: Tradeoff between robustness and replicative lifespan

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2013Dec5 comments
M2-8 has a dilution bias and was not fitted correctly in this plot.
M32 is a tricky strain that we repeated at least 5 times.
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Large Cv/Cb indicate better survival ship beyond H2O2-induced LOH. The negative correlation indicates a trade off
between Cv/Cb and RLS. 

plot( tb$Cv.vs.Cb ~ tb$ARLS, pch=19, col="red", main="H2O2-LOH ~ ARLS, 20130531" )
 text( tb$ARLS, tb$Cv.vs.Cb, tb$strain)
 m = lm(tb$Cv.vs.Cb ~ tb$ARLS )
 abline( m, col="blue")
 summary(m)
 text(33, 3, "R2=0.37 p=0.035")

Small L0 indicates better asymmetry. Large Cv/Cb indicates better tolerance to H2O2 or
more sensitive to H2O2. So, this negative correlation actually indicates a positive relationship
between Cv/Cb and mitotic asymmetry. 

 plot( tb$Cv.vs.Cb ~ tb$L0.all , pch=19, col="red", main="H2O2-LOH ~ mitotic asymmetry, 20130531" )
 text( tb$L0.all, tb$Cv.vs.Cb, tb$strain)
 m = lm(tb$Cv.vs.Cb ~ tb$L0.all )
 abline( m, col="blue")
 summary(m)
 text(0.2, 3.5, "R2=0.42 p=0.031")

Updated on 2013 June 18. I switched x-y axis for more clear presentation.

Updated on 2013 June 18.

Conclusions:  
 Cv/Cb ~(-)~ ARLS
 Tc/Tg ~(-)~ ARLS
  G       ~(-)~ ARLS
Morphological robustness ~(-)~ RLS ?
Growth fitness ~(+)~ RLS ?


Reference:
_2013May31-H2O2LOH.R
_2013June18-H2O2LOH.R