Thursday, April 15, 2021

GTEx tissue and cell specific gene networks in humans


Some of the best multi-view data are at NCBI GTEx site. 

https://www.gtexportal.org/home/datasets

 

These data sets however are quite complicated and need substantial analysis because they can be fed into deep learning models. 

 

nano -w GTEx_Analysis_2017-06-05_v8_RNASeQCv1.1.9_gene_reads.gct 

This file seems to show Ensembl gene ids and counts

There are genotypic data, so we can infer how SNPS -> expression -> phenotypic changes

The GTEx Consortium atlas of genetic regulatory effects across human tissues

https://www.biorxiv.org/content/10.1101/787903v1

ML papers using GTEx
* standard ML outperform deep learning
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-020-3427-8 

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