Showing posts with label ML4 comp biol. Show all posts
Showing posts with label ML4 comp biol. Show all posts

Monday, September 1, 2025

MLCB25 Machine Learning for Computational Biology, Manolis KellisManolis Kellis

 

MIT Course announcement: Machine Learning for Computational Biology hashtagMLCB25
Fall'24 Lecture Videos: https://lnkd.in/efSvp7hY
Fall'24 Lecture Notes: https://lnkd.in/eWBAxQHk
(a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome topology, epigenomics, regulatory networks.
(b) Proteins: Protein language models, structure and folding, protein design, cryo-EM, AlphaFold2, transformers, multimodal joint representation learning.
(c) Therapeutics: Chemical landscapes, small-molecule representation, docking, structure-function embeddings, agentic drug discovery, disease circuitry, and target identification.
(d) Patients: Electronic health records, medical genomics, genetic variation, comparative genomics, evolutionary evidence, patient latent representation, AI-driven systems biology.
Foundations and frontiers of computational biology, combining theory with practice. Generative AI, foundation models, machine learning, algorithm design, influential problems and techniques, analysis of large-scale biological datasets, applications to human disease and drug discovery.
First Lecture: Thu Sept 4 at 1pm in 32-144
With: Prof. Manolis Kellis, Prof. Eric Alm, TAs: Ananth Shyamal, Shitong Luo
Course website: https://lnkd.in/eemavz6J