Jianhua Xing's paper governing equations for cell phenotypic transition, data science + systems biology
strength:
The governing vector field A is remarkably similar the network matrix in Linear system control
The Gaussian noise term models a white noise, which may be incorporated into network control models.
The path approach is similar to the Qing Nie's paper which use information entropy to compare choices of pathes.
Weakness:
I was disappointed that the principal component was used in the analysis. It is also not obvious how driver genes can be identified. So, it is a theory with no apparent practice guidance?
My summary:
It is a good theoretic paper, as Xing focuses on the big picture.
