predicting new viral variants

 

Flagship unwraps new AI biotech that looks to predict variants before they’re here

https://endpts.com/flagship-unwraps-new-ai-biotech-that-looks-to-predict-variants-before-theyre-here/

Shedden et al, 2008, Nature medicine, gene expression based survival prediction in lung adenocarcinoma

Shedden et al, 2008, Nature medicine, gene expression based survival prediction in lung adenocarcinoma
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667337/

health disparity, expression dataset, supposed to have ethnic group information. 

several classifier algorithms were used. cross-validation were applied, ROC curves used. 

good reference for my lifespan prediction study. 

Method A (Gene clusters and ridge regression)

binary tree-structured vecgor quantization -> binary cluster tree using expression profiles

Method B (Stratified Cox model on univariately selected genes)

Method C (clustering of samples combined with minimum gene selection).

Method D. (clustering of samples combined with minimum gene selection).