Cancer genomics resource

McFarland, Sunyaev, Mirny PNAS, 2013 impact of deleterious passernger mutations on cancer progression.

Catalogue of Somatic Mutations in Cancer (COSMIC) and The Cancer Genome Atlas (TCGA). We classified them as driver and passenger mutation groups and then characterized their effects

using PolyPhen, a tool widely used in population and medical genetics to predict the damaging effect of missense mutations (15).

Ref 15: Boyko AR, et al. (2008) Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet 4(5):e1000083.

COSMIC http://cancer.sanger.ac.uk/cosmic

TCGA: http://cancergenome.nih.gov/

https://tcga-data.nci.nih.gov/tcga/tcgaDownload.jsp
TCGA offer BAM sequence data.