Tuesday, November 17, 2020

Cooper 2006, BMC, Distinguishing between linear and exponential cell growth during the division cycle: Single-cell studies, cell-culture studies, and the object of cell-cycle research

 

Cooper, 2006.  Distinguishing between linear and exponential cell growth during the division cycle: Single-cell studies, cell-culture studies, and the object of cell-cycle research


This is a commentary. Cooper seems to be a biologist, argues that mass measurement is more accurate on single cell study to understand growth 'law'. This seems to be contrary to the statistical physics argument. The commentary is mostly philosophical and are based on the best-fit argument of experimental data. 

Cooper main argument that exponential growth is the universal growth law also assumes abundant resources. Cooper said that linear growth is due to experimental measurement limitation also did not take ecological constraints and biological competition into account. 

Cooper cited Michison's linear growth model based on 4 decades of works. 


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