R15 proposals in NIA

1R15AG053879-01
ROLE OF CIRCADIAN CLOCK COMPONENTS IN APOPTOSIS AND TAUOPATHY IN DROSOPHILA

https://projectreporter.nih.gov/project_info_details.cfm?aid=9171076&icde=39147502&ddparam=&ddvalue=&ddsub=&cr=27&csb=default&cs=ASC&pball=

CELL SIGNALING AND RESISTANCE TO OXIDATIVE STRESS: EFFECTS OF AGING AND EXERCISE.
https://projectreporter.nih.gov/project_info_description.cfm?aid=9225339&icde=39147502&ddparam=&ddvalue=&ddsub=&cr=8&csb=FY&cs=DESC&pball=

1R15AG050218-01A1
TESTING DIRECT EFFECTS OF REPRODUCTION ON LIFESPAN WITH CONTROLLED FEEDING IN GRASSHOPPERS
https://projectreporter.nih.gov/project_info_description.cfm?aid=9093113&icde=39147502&ddparam=&ddvalue=&ddsub=&cr=11&csb=FY&cs=DESC&pball=

1R15AG052933-01
THE ROLES OF SPHINGOLIPIDS IN STRESS RESPONSE AND HEALTHY AGING.
https://projectreporter.nih.gov/project_info_description.cfm?aid=9099409&icde=39147502&ddparam=&ddvalue=&ddsub=&cr=16&csb=FY&cs=DESC&pball=

1R15AG052149-01
REGULATION OF THE C. ELEGANS HEAT SHOCK RESPONSE BY LST-3
https://projectreporter.nih.gov/project_info_description.cfm?aid=9022936&icde=39147502&ddparam=&ddvalue=&ddsub=&cr=38&csb=default&cs=ASC&pball=

biogrid PPI

read my old codes:

applejack:qin.biogrid.code hqin$ pwd

/Users/hqin/data/biogrid/qin.biogrid.code

My code took 'physical' interactions from biogrid, and found only unique interactions.

standardize IC50 like pH?

https://www.collaborativedrug.com/buzz/2014/07/14/why-using-pic50-instead-of-ic50-will-change-your-life/

multiplicity of eigen value

The number of linearly independent eigenvectors associated with a given eigen value $lambda$ is called the geometric multiplicity of eigenvalue $lambda$.

matrix Jordan cannonical form and eigen values

http://mathworld.wolfram.com/JordanCanonicalForm.html

Eigen values in Jordan cannobucak form of matrix

estimate protein interactions based on network evolution

estimate protein interactions based on network evolution

https://www.sciencedirect.com/science/article/pii/S037843711730924X

qin 2003 pnas

*** naked mole rat, non-aging model?

elife:

Naked mole-rat mortality rates defy

Gompertzian laws by not increasing with

age

J Graham Ruby, Megan Smith, Rochelle Buffenstein*

Calico Life Sciences LLC, South San Francisco, United States

TODO: exponential signal + white noises :: exponential fitting
Gompertiz signal + white noises :: exponential fitting vs Gompertz fitting. Perhaps, there is just not enough statistical power?

Gym openAI

https://gym.openai.com/

open data sets

datasets for deep learning

https://www.analyticsvidhya.com/blog/2018/03/comprehensive-collection-deep-learning-datasets/

NIH uncolicited applications

Did you know that the majority of funded NIH proposals are unsolicited?  That is, they are not in response to a specific funding opportunity announcement!

https://www.niaid.nih.gov/grants-contracts/unsolicited-investigator-initiated-research  although this guidance is specific to NIAID (allergy and infectious disease), the same applies to almost all of NIH – especially NCI – the wealthiest of all at NIH.

Please see the attached presentation from Program Officer, Dr. David Berrigan at NCI.  Last week at meetings at UTK, he took us through the top 10 list of research gems from the Division of Cancer Control and Population Sciences.  These are applicable to anywhere at NIH, not just NCI.

Zoom course instruction with iPad

1) Zoom on MacBook, sharescreen with iPad through airplay or cable. (Sometimes, airplay or cable does not work).

2) Zoom on Mackbook, iPad screen shared with Zoom App.  Make sure microphone is muted. Record on both Mackbook.  Make sure personal app, emails are closed.

journal of computational biology

Journal of Computational Biology Special Issue: The 13th International Symposium on Bioinformatics Research and Applications (ISBRA2017) This Special Issue includes a selection of papers presented at the 13th International Symposium on Bioinformatics Research and Applications (ISBRA 2017) which was held in Honolulu, Hawaii on May 30–June 2, 2017. ISBRA provides a forum for the exchange of ideas and results among researchers, developers, and practitioners working on all aspects of bioinformatics and computational biology and their applications. Enjoy FREE ACCESS through April 9, 2018. Read Now: Preface: 13th International Symposium on Bioinformatics Research and Applications (ISBRA 2017) Zhipeng Cai, Pavel Skums, Alexander Zelikovsky  Read Now Reconstructing One-Articulated Networks with Distance Matrices Kuang-Yu Chang, Yun Ciu, Siu-Ming Yiu, Wing-Kai Hon  Read Now ICON-MIC: Implementing a CPU/MIC Collaboration Parallel Framework for ICON on Tianhe-2 Supercomputer Zihao Wang, Yu Chen, Jingrong Zhang, Lun Li, Xiaohua Wan, Zhiyong Liu, Fei Sun, Fa Zhang  Read Now Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry Michał Aleksander Ciach, Mateusz Krzysztof Łącki, Błażej Miasojedow, Frederik Lermyte, Dirk Valkenborg, Frank Sobott, Anna Gambin  Read Now A Median Solver and Phylogenetic Inference Based on Double-Cut-and-Join Sorting Ruofan Xia, Yu Lin, Jun Zhou, Bing Feng, Jijun Tang  Read Now Convolutional Neural Network for Histopathological Analysis of Osteosarcoma Rashika Mishra, Ovidiu Daescu, Patrick Leavey, Dinesh Rakheja, Anita Sengupta  Read Now Beta-Barrel Detection for Medium Resolution Cryo-Electron Microscopy Density Maps Using Genetic Algorithms and Ray Tracing Albert Ng, Dong Si  Read Now An Optimized Method for Bayesian Connectivity Change Point Model Xiuchun Xiao, Bing Liu, Jing Zhang, Xueli Xiao, Yi Pan  Read Now Unbiased Taxonomic Annotation of Metagenomic Samples Bruno Fosso, Graziano Pesole, Francesc Rosselló, Gabriel Valiente  Read Now

BioID2 protein interaction detection

BioID2
http://www.molbiolcell.org/content/early/2016/02/11/mbc.E15-12-0844.full.pdf 

Finding your inner modler

UIC .NSF wortkshop, Finding your inner modler

microbiology plate imaging systems

https://800ezmicro.com/equipment/anaerobic-hypoxic-systems/32-petrifoto-plate-imaging-system.html