science advance
This site is to serve as my note-book and to effectively communicate with my students and collaborators. Every now and then, a blog may be of interest to other researchers or teachers. Views in this blog are my own. All rights of research results and findings on this blog are reserved. See also http://youtube.com/c/hongqin @hongqin
Monday, August 31, 2020
gene ontology dowload, slim versus obo
OBO versus Slim
there are confusion yeast subset, GOSLIm (is the a subset of yeast GO or full-genome coverage). Guo think Goslim is a partial coverage of the yeast genome. The http://geneontology.org/docs/go-subset-guide/ seem to suggest that yeast genome-GO is call "slim".
It seems OBO is a human readable format.
http://geneontology.org/docs/go-subset-guide/
http://geneontology.org/docs/download-ontology/#subsets
Ghafari suggests:
https://sites.google.com/view/yeastgenome-help/useful-sgd-links?authuser=0 which linked to a FTP site at sgd: http://sgd-archive.yeastgenome.org/. and https://downloads.yeastgenome.org/latest/sgd.gaf.gz
Guo confirmed that *gaf file is what he used.
GAF format is at
http://geneontology.org/docs/go-annotation-file-gaf-format-2.1/
But, GAF files is gene-2-GO mapping. Not the GO_tree.
It seems JASON files contain 'graph', 'node' in its structure.
https://ontobio.readthedocs.io/en/latest/notebooks.html
Jupyternoteook https://github.com/biolink/ontobio
TODO: read graph based DNN to see how graph is converted to connection of layers.
Guo suggests GO-CAM, a nature comment with download link
http://current.geneontology.org/products/ttl/index.html
Sunday, August 30, 2020
Friday, August 28, 2020
Wednesday, August 26, 2020
GRFP deadlines 2021
important days
https://www.nsfgrfp.org/applicants/important_dates
life science Oct 19
computer science Oct 20
3 Letters, October 30
Saturday, August 22, 2020
parrots lifespan and genomes
Kakapo, lifespan 95 years
Parrots, also known as psittacines /ˈsɪtəsaɪnz/,[1][2] are birds of the roughly 393 species in 92 genera comprising the order Psittaciformes, found mostly in tropical and subtropical regions.
https://en.wikipedia.org/wiki/Parrot
https://en.wikipedia.org/wiki/Genomic_evolution_of_birds
https://b10k.genomics.cn/species.html
https://academic.oup.com/gigascience/pages/avian_genomes_collection
Sunday, August 16, 2020
biology student researcher advertisment
Biology/Biochemistry major needed for a gene network + deep learning research project on longevity modeling and prediction
I am looking for an undergraduate biology/biochemistry major interested in teaming up with computer science students to work on using deep learning to model gene networks and lifespan of cells. A relevant publication is “Using deep learning to model the hierarchical structure and function of a cell”, Nature Methods, 2018, https://www.nature.com/articles/nmeth.4627.
Relevant knowledge of the biology/biochem student may include a good understanding of the molecular mechanisms of genetic materials, replication, gene expression, protein biosynthesis and function, metabolism, cellular organization. Most importantly, this student researcher should be eager to learn new concepts and skills. The biology student is expected to work on the molecular biology aspect of this inter-disciplinary project, and receive hourly pay. Computational skill is not required for this biology/biochem student, but we hope he/she is willing to learn computational skills.
If interested, please send your resume and unofficial transcripts to xxx@utc.edu
Monday, August 10, 2020
Friday, August 7, 2020
Microsoft Research Ada Lovelace Fellowship
Nominations are now open for the 2021 Microsoft Research Ada Lovelace Fellowship and Microsoft Research PhD Fellowship. Doctoral students must be nominated by the department chair’s office in their field of study by August 14, 2020. Students will then be contacted to submit their proposals by September 21, 2020.
The Microsoft Research Ada Lovelace Fellowship aims to increase the pipeline of diverse talent receiving advanced degrees in computing-related fields by providing a research funding opportunity for doctoral students who are underrepresented in the field of computing. This includes those who self-identify as a woman, African American, Black, Hispanic, Latinx, American Indian, Alaska Native, Native Hawaiian, Pacific Islander, person with a disability, and/or LGBTQI+. The award for second year PhD students covers tuition and fees for three years and a $42,000 USD stipend annually.
The Microsoft Research PhD Fellowship is for third year doctoral students also attending a university in the United States, Canada, or Mexico who are conducting research in computing-related fields. The award covers tuition and fees for two years and includes an annual $42,000 USD stipend.
For both awards, students’ research must be closely related to the general research areas carried out by researchers at Microsoft. In addition to the funding mentioned above, Microsoft Research will host a two-day workshop next fall where fellows will meet with Microsoft researchers and other top students to share their research in person and/or virtually as local and national health and safety guidance advises.
You can read more about the fellowships and find nomination instructions at https://aka.ms/ada-lovelace-
Ada Lovelace Fellowship - Twitter, Facebook and Instagram
PhD Fellowship - Twitter, Facebook and Instagram
We hope you will help us spread the word about these fellowships! We encourage you to share this announcement directly with your students and department chair’s office, on social media, and/or via topically relevant email lists.
For questions, please contact Microsoft Research Fellowships msfellow@microsoft.com.
For more information on all of our academic programs, visit https://aka.ms/academic-
Thank you, |
Chair, MSR Ada Lovelace Fellowship Principal Researcher, Microsoft Research | Chair, MSR PhD Fellowship Principal Researcher, Microsoft Research |
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