Monday, August 31, 2020

gene ontology dowload, slim versus obo

 

OBO versus Slim

there are confusion yeast subset, GOSLIm (is the a subset of yeast GO or full-genome coverage). Guo think Goslim is a partial coverage of the yeast genome. The http://geneontology.org/docs/go-subset-guide/ seem to suggest that yeast genome-GO is call "slim". 


It seems OBO is a human readable format. 


http://geneontology.org/docs/go-subset-guide/

http://geneontology.org/docs/download-ontology/#subsets


Ghafari suggests: 

https://sites.google.com/view/yeastgenome-help/useful-sgd-links?authuser=0  which linked to a FTP site at sgd:  http://sgd-archive.yeastgenome.org/. and https://downloads.yeastgenome.org/latest/sgd.gaf.gz 


Guo confirmed that *gaf file is what he used. 

GAF format is at 

http://geneontology.org/docs/go-annotation-file-gaf-format-2.1/

But, GAF files is gene-2-GO mapping. Not the GO_tree. 

It seems JASON files contain 'graph', 'node' in its structure. 

https://ontobio.readthedocs.io/en/latest/notebooks.html

Jupyternoteook https://github.com/biolink/ontobio 

TODO: read graph based DNN to see how graph is converted to connection of layers. 

Guo suggests GO-CAM, a nature comment with download link

http://current.geneontology.org/products/ttl/index.html




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