Showing posts with label Virginia Tech. Show all posts
Showing posts with label Virginia Tech. Show all posts

Thursday, August 15, 2013

cell size control

cell cycle regulation OR growth rate regulation?

Do smaller cells have longer G1 phases?
negative correlation bw G1 length and cell size

antibody screen for size sencors

identify drugs that weakens negative correlation bw size and cell cycle, size and growth rate.

mTOR affect size and growth rate.

some kind of integral feed back loops might be involved.



Albert Goldbeter, Vatech talk


Gerard and Goldbeter 2012 argued that cell cycle is a limit cycle. This seems to imply that cell cycle would go indefinitly.  An aging model would require a damned cycle.
Gerard Goldbeter Math Model Nat Phenom, 2012