I study computational and quantitative biology with a focus on network aging. This site is to serve as my note-book and to effectively communicate with my students and collaborators. Every now and then, a blog may be of interests to other researchers or teachers. Views in this blog are my own. All rights of research results and findings on this blog are reserved. See also http://youtube.com/c/hongqin
Friday, June 17, 2016
Measurement and Modeling of Drugs in Tissues (Organized in Cooperation with International Society of Anti-Infective Pharmacology (ISAP))
SESSION 044-C - Measurement and Modeling of Drugs in Tissues (Organized in Cooperation with International Society of Anti-Infective Pharmacology (ISAP))
June 17, 2016, 12:45 - 4:15 PM
Westin, Grand Ballroom A
Anti-infective pharmacokinetics and pharmacodynamic (PK/PD) modeling traditionally relies on serum or plasma concentration-time data to define exposure-response relationships. Data derived from the blood compartment may or may not accurately reflect target tissue data. This course aims to review current and novel approaches to better quantify target tissue PK/PD. An improved understanding of tissue PK/PD measurement and modeling can help to optimize dosage regimen selection for infections in accessible and restricted compartments.