Saturday, April 24, 2021

Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution

Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution 

https://www.cell.com/action/showPdf?pii=S2666-3791%2821%2900073-2

Measles led to poly-clonal antibody with multiple epitope response, so the antigenic shift has a very small chance. 

SARS-CoV2 and Influenza led to focused antibody response, so antigenic shift has a higher chance. 

Theoretically, a vaccine with poly-epitope response would be a better vaccine. 



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