PlosGenetics, Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes, Slavé Petrovski et al, 2013
The paper measured mutations using exome sequencing, conduct network analysis.
http://channelopathist.net/2013/10/06/mutation-intolerance-why-some-genes-withstand-mutations-and-others-dont/?utm_source=buffer&utm_campaign=Buffer&utm_content=buffer94829&utm_medium=twitter
http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003709
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