Wednesday, December 10, 2014

Shedden et al, 2008, Nature medicine, gene expression based survival prediction in lung adenocarcinoma

Shedden et al, 2008, Nature medicine, gene expression based survival prediction in lung adenocarcinoma
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667337/

health disparity, expression dataset, supposed to have ethnic group information. 

several classifier algorithms were used. cross-validation were applied, ROC curves used. 


good reference for my lifespan prediction study. 


Method A (Gene clusters and ridge regression)
binary tree-structured vecgor quantization -> binary cluster tree using expression profiles

Method B (Stratified Cox model on univariately selected genes)

Method C (clustering of samples combined with minimum gene selection).

Method D. (clustering of samples combined with minimum gene selection).

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