Wednesday, September 9, 2015

(todo) Genetic evidence for common pathways in human age-related diseases


Genetic evidence for common pathways in human age-related diseases

http://onlinelibrary.wiley.com/doi/10.1111/acel.12362/suppinfo

  1. Johnson2015 Aging Cell

Table 2 show a list of gene on NCBI
One of the supplementary table listed a list of genes associated with longevity in a GWAS.
Only two genes overlap between these two list.

Todo:
1a) retrieve FASTA protein sequences of these human genes
1b) identify interacting partners of these human proteins, and retrieve their protein FASTA sequences
2) blast yeast genome to identify their homologs
3) any interesting phenotypes of the yeast mutants?

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