Friday, July 15, 2016

cyclin C and mitochondria

 ROS-induced degradation of Med13 by SCFGrr1 mediates mitochondrial fragmentation and cell death.

D. Stieg  ; ... K. Cooper 

cyclin c --> mitochondria fission

ROS stress --> MAPK

No stress: cyclin C in nuclear
Stress translocate cyclin C to cytosal.

So, cyclinC may influence yeast lifespan through its influence on mitochondria? 

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