ROS-induced degradation of Med13 by SCFGrr1 mediates mitochondrial fragmentation and cell death.
D. Stieg ; ... K. Cooper
ROS stress --> MAPK
No stress: cyclin C in nuclear
Stress translocate cyclin C to cytosal.
http://www.ncbi.nlm.nih.gov/pubmed/25609094
So, cyclinC may influence yeast lifespan through its influence on mitochondria?
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