http://paup.csit.fsu.edu/paupfaq/faq.html
http://peter.unmack.net/molecular/programs/paup.command.blocks.html
http://phylo.bio.ku.edu/slides/lab5ML/lab5ML.html
For maximum likelihood estimation, I see several ways to set it up in PAUP.
ML Analysis in PAUP by Peter Unmack
[!
Likelihood settings from best-fit model (GTR+I+G) selected by AIC in Modeltest
3.7 on Tue Mar 13 23:03:48 2007]
begin paup;
set criterion=like;
set autoclose=yes;
set root = outgroup;
outgroup fish1 fish2 etc;
set storebrlens=yes;
set increase=auto;
log file=PeterML.log;
Lset Base=(0.2892 0.2928 0.1309) Nst=6
Rmat=(3.7285 46.5293 1.3888 2.3793 16.4374) Rates=gamma
Shape=0.9350 Pinvar=0.5691;
hsearch addseq=random nreps=5 swap=tbr;
savetrees file=datasetname.cb.ml.tree.nex format=altnex brlens=yes
maxdecimals=6;
end;
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