Saturday, August 10, 2013

E coli aging !!

Suckjoon Jun and Minsu Kim: 

CFU viability is exponential, but RLS is Gompertz. When SOS is knocked out, RLS become exponential.

RLS for E coli is measured in good growth condition, and CLS for E coli is measured in depleted nutrient condition. It is possible that CLS condition overwhelm network buffering and resulted in a network with too little redundancy.  On the other hand,  aging was able to manifest itself during growth, because the external 'insults' are below the 'critical' point for network robustness.

Craig Skinner and Su-ju Lin, 2010 AMB review on CR





CR on E coli aging
http://precedings.nature.com/documents/2071/version/1






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