Monday, November 20, 2017

cellular aging in immune systems

purified monocytes, B cells and T cells, from young and old donors

"This signature is borne by memory CD8+ T cells, which exhibited an aging-related loss in binding of NF-κB and STAT factors. Thus, our study provides a unique and comprehensive approach to identifying candidate biomarkers and provides mechanistic insights into aging-associated immunodeficiency."

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