purified monocytes, B cells and T cells, from young and old donors
http://jem.rupress.org/content/early/2017/09/12/jem.20170416
"This signature is borne by memory CD8+ T cells, which exhibited an aging-related loss in binding of NF-κB and STAT factors. Thus, our study provides a unique and comprehensive approach to identifying candidate biomarkers and provides mechanistic insights into aging-associated immunodeficiency."
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