Saturday, June 26, 2021

quantum speed up on alignment or alignment sequence analysis

 

alignment is a score matrix, so matrix method might speed the best alignment? 

https://www.youtube.com/watch?v=p2hZL38tqAs


quantum solution on the maximum unique match might be a good starting point. 

https://en.wikipedia.org/wiki/Sequence_alignment#Maximal_unique_match


alignment - free sequence 

https://bioinformaticsreview.com/20170704/role-of-information-theory-chaos-theory-and-linear-algebra-and-statistics-in-the-development-of-alignment-free-sequence-analysis/

Square of Ajacency matrice give estimation of path























Quantum Walk and Graph search. 


Qin: sequence alignment can be conerted all-2-all adjacent matrix. So, sequence alignment then might become a quantum walk and graph search problem. 


Friday, June 25, 2021

GTEx factorization tissue specific regulation

 

sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02129-6




UTC DUO VPN instructions

 

Starting 7/1/2021 access to UTC using the VPN will require the use of your UTCID, password, and Duo 2FA client.  If you are using your UTCID and already have 2FA setup, the only change should be a prompt for you to send a Duo push to your Duo client.

If you are using your simcenter account to login, you will need to use your UTCID and password instead.  We have tried to ensure that affiliates w/o UTCIDs have them generated by Central IT and sent to the user.

LINUX COMMAND LINE USERS will no longer BE ABLE TO USE THE COMMAND LINE to connect to the VPN.  You will need to install the "UI" version of the package for your operating system and use it to connect.  See Central IT's link below for more details.


Duo Setup

VPN Setup

Thursday, June 24, 2021

gtex aspera command line, ts117

reference: 

https://www.ibm.com/support/pages/downloading-data-ncbi-command-line 


conda create --name aspera

conda active aspera


-bash-4.2$ wget https://d3gcli72yxqn2z.cloudfront.net/connect_latest/v4/bin/ibm-aspera-connect-3.11.2.63-linux-g2.12-64.tar.gz

--2021-06-24 12:32:34--  https://d3gcli72yxqn2z.cloudfront.net/connect_latest/v4/bin/ibm-aspera-connect-3.11.2.63-linux-g2.12-64.tar.gz

Resolving d3gcli72yxqn2z.cloudfront.net (d3gcli72yxqn2z.cloudfront.net)... 13.249.125.124, 13.249.125.227, 13.249.125.202, ...

Connecting to d3gcli72yxqn2z.cloudfront.net (d3gcli72yxqn2z.cloudfront.net)|13.249.125.124|:443... connected.

HTTP request sent, awaiting response... 200 OK

Length: 38715569 (37M) [application/gzip]

Saving to: ‘ibm-aspera-connect-3.11.2.63-linux-g2.12-64.tar.gz’


100%[===========================================================================================================================>] 38,715,569  80.1MB/s   in 0.5s   


2021-06-24 12:32:35 (80.1 MB/s) - ‘ibm-aspera-connect-3.11.2.63-linux-g2.12-64.tar.gz’ saved [38715569/38715569]


-bash-4.2$ ll


(aspera) -bash-4.2$ sh ibm-aspera-connect-3.11.2.63-linux-g2.12-64.sh 


Installing IBM Aspera Connect


Deploying IBM Aspera Connect (/home/hqin/.aspera/connect) for the current user only.


Install complete.


(aspera) -bash-4.2$ cd /scr/hqin/gtex/

(aspera) -bash-4.2$ ls

(aspera) -bash-4.2$ /home/hqin/.aspera/connect/bin/ascp  -QTr -l 300M -k 1 -i /home/hqin/.aspera/connect/etc/asperaweb_id_dsa.openssh -W private-key-here dbtest@gap-upload.ncbi.nlm.nih.gov:data/instant/hongqin/82927 .

Release_Notes.phs000424.GTEx.v8.p2.MULTI.pdf.                                                                                      100%  432KB  5.0Mb/s    00:00    

Study_Report.phs000424.GTEx.v8.p2.MULTI.pdf.n                                                                                      100%   94KB  5.0Mb/s    00:00    

manifest_phs000424.GTEx.v8.p2.c1.GRU.pdf.ncbi                                                                                      100%   43KB  5.0Mb/s    00:00    

phs000424.v8.pht002740.v8.GTEx_Subject.data_d                                                                                      100% 1200    5.0Mb/s    00:00    

phs000424.v8.pht002740.v8.p2.GTEx_Subject.MUL                                                                                      100% 6000    5.0Mb/s    00:00    

phs000424.v8.pht002740.v8.p2.GTEx_Subject.var                                                                                      100% 3264    5.0Mb/s    00:00    

phs000424.v8.pht002741.v8.GTEx_Sample.data_di                                                                                      100%  992    5.0Mb/s    00:00    

phs000424.v8.pht002741.v8.p2.GTEx_Sample.MULT                                                                                      100%  271KB  5.0Mb/s    00:01    

phs000424.v8.pht002741.v8.p2.GTEx_Sample.var_                                                                                      100% 2032    5.0Mb/s    00:01    

phs000424.v8.pht002742.v8.GTEx_Subject_Phenot                                                                                      100%   89KB  5.0Mb/s    00:01    

phs000424.v8.pht002742.v8.p2.GTEx_Subject_Phe                                                                                      100%  293KB 11.2Mb/s    00:01    

phs000424.v8.pht002742.v8.p2.c1.GTEx_Subject_                                                                                      100%  197KB 11.2Mb/s    00:01    

phs000424.v8.pht002743.v8.GTEx_Sample_Attribu                                                                                      100%   26KB 11.2Mb/s    00:01    

phs000424.v8.pht002743.v8.p2.GTEx_Sample_Attr                                                                                      100%  124KB 11.2Mb/s    00:01    

phs000424.v8.pht002743.v8.p2.c1.GTEx_Sample_A                                                                                      100% 3617KB 23.6Mb/s    00:02    

phg000219.v4.GTEx_Pilot_Illumina5M.genotype-c                                                                                      100%  698MB  292Mb/s    00:24    

phg000219.v4.GTEx_Pilot_Illumina5M.genotype-o                                                                                       14% 5337MB  290Mb/s    15:44 ETAc

......

(aspera) -bash-4.2$ Completed: 1448373288K bytes transferred in 40722 seconds

 (291366K bits/sec), in 59 files, 7 directories; 16 files skipped or empty.

fine grained or not,

 

Your "Flamingo" is My "Bird": Fine-Grained, or Not 

https://github.com/PRIS-CV/Fine-Grained-or-Not


https://arxiv.org/abs/2011.09040

Sunday, June 20, 2021

research.gov margin and line space problems

 lines problem can be fixed by setting exact point, or at least 12 points. 

margin problems are often due to auto-formating in special cases, such as ending, bulleting points. 

https://www.galoisrepresentations.com/2019/09/06/nsf-application-tips-latex-edition/

make line at least 12 pt in WORD generally solve this problem. 

It turns out that Adobe File Reduce can change the line space which will lead to warnings in resaerch.gov. Interestingly, WORD-saved pdf can pass the line-space check. Because the WORD file has a size limit of 10M, so I have to use small sized figures (save png as jpg, and then re-upload the figure to WORD). I used Photoshop to convert png to jpg to reduce WORD file size. 


Saturday, June 19, 2021

‘invariant rate of ageing’ hypothesis

invariant rate of ageing

 https://www.nature.com/articles/s41467-021-23894-3

https://github.com/fercol/ColcheroEtal2021NatComm



CVPR meeting notes

morphing attack detection  

https://www.christoph-busch.de/projects-mad.html

https://ieeexplore.ieee.org/document/9246583

https://biolab.csr.unibo.it/FVCOnGoing/UI/Form/BenchmarkAreas/BenchmarkAreaDMAD.aspx

intel analytics zoo

https://github.com/intel-analytics/analytics-zoo

normalization method in dnn

https://normalization-dnn.github.io/ 


https://github.com/QinLab/network-controllability

https://www.youtube.com/watch?v=bwIgpxmWnWM

https://sites.google.com/view/fgvc8

https://fadetrcv.github.io/2021/


neural network architecture search:  https://cvpr21-nas.com/


https://www.es.ele.tue.nl/cvpm21/program.pdf

microscopic image:  https://cvmi2021.github.io/


The Cell Tracking and Mitosis Challenge

https://github.com/JonathonLuiten/TrackEval/blob/master/docs/MOTChallenge-Official/Readme.md






Thursday, June 17, 2021

facebook deepfake detection

 https://www.theregister.com/2021/06/17/facebook_deepfake_identification/


https://github.com/vishal3477/Reverse_Engineering_GMs



Tweetable mathematical art with R

 

https://fronkonstin.com/2018/09/06/tweetable-mathematical-art-with-r/


Monday, June 14, 2021

aging clock

Royal society medicine webinar 

sheep clock, universal mammalian clock

ribosomal DNA is a good clock, but not conserved among species

tortoise and lizard? 

in human, female aging advantage is more pronounced in liver tissues.  So far, epi aging clock is not related to fertility in human. 

Shiqing Cai

https://www.nature.com/articles/s41586-020-2037-y











Sunday, June 13, 2021

tweet sentiment pytorch

 


https://github.com/BinaryBlackhole/Pytorch-implementation-twitter-sentiment-analysis-using-RNN



linear regression, MLE versus Bayesian MAP

 https://towardsdatascience.com/frequentist-vs-bayesian-approaches-in-machine-learning-86ece21e820e



Monday, June 7, 2021

biological network across scales

 

https://reintegratingbiology.org/wp-content/uploads/2019/12/Netwoks-Across-Scales-Gustavo-Caetano-Anolles.pdf


Friday, June 4, 2021

COVID19 vaccination and testing data

 


https://github.com/govex/COVID-19


Baez, category data, permutation

 https://math.ucr.edu/home/baez/

https://twitter.com/johncarlosbaez

permutations: https://math.ucr.edu/home/baez/permutations/



NSF Computational Data-Enabled Science and Engineering


NSF has released a new version of its Computational Data-Enabled Science and Engineering program. The CDS&E program encourages research that pushes the envelope of science and engineering through computation and data, welcoming proposals in any area of research supported by the participating divisions. A proposal may address topics that develop or enable interactions among theory, computing, experiment, and observation to achieve progress on hitherto intractable science and engineering problems.

 

The participating divisions and their deadlines are below. Each division has specific emphasis areas. See the solicitation for details: https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505920. I strongly encourage everyone whose work falls under one of these divisions to explore the solicitation and see if it would make sense to prepare a proposal!

 

Directorate

Division and Program

Submission Window or Target Date

ENG

Division of Chemical, Bioengineering, Environmental, and Transport Systems

  September 01, 2021 - September 15, 2021

  September 01- September 15, Annually Thereafter

ENG

Division of Civil, Mechanical and Manufacturing Innovation

  September 01, 2021 - September 15, 2021

  September 01- September 15, Annually Thereafter

MPS

Division of Mathematical Sciences

  September 01, 2021 - September 15, 2021

  September 01- September 15, Annually Thereafter

MPS

Division of Chemistry - Chemical Catalysis (CAT), Chemical Structure, Dynamics and Mechanisms-A (CSDM-A), Chemical Structure Dynamics and Mechanisms-B (CSDM-B), Chemical Synthesis (SYN), Chemical Theory, Models and Computational Methods (CTMC)

  September 01, 2021 - September 30, 2021

  September 01 - September 30, Annually Thereafter

MPS

Division of Materials Research

  October 15, 2021

  October 15, Annually Thereafter

MPS

Division of Astronomical Sciences - Advanced Technologies and Instrumentation

  October 01, 2021 - November 15, 2021

  October 01 - November 15, Annually Thereafter

CISE

Office of Advanced Cyberinfrastructure

  October 01, 2021 - November 01, 2021

  October 01 - October 31, Annually Thereafter

ENG

Division of Electrical, Communications and Cyber Systems

  October 01, 2021 - November 01, 2021

  October 01 - October 31, Annually Thereafter

MPS

Division of Chemistry - Chemical Measurement and Imaging (CMI), Chemistry of Life Processes (CLP), Environmental Chemical Sciences (ECS), and Macromolecular, Supramolecular and Nanochemistry (MSN)

  October 01, 2021 - November 01, 2021

  October 1 - October 31, Annually Thereafter

MPS

Division of Astronomical Sciences - Astronomy and Astrophysics Research Grants

  October 01, 2021 - November 15, 2021

  October 01 - November 15, Annually Thereafter

MPS

Division of Physics: Investigator-Initiated Research Projects

Per specific program


  




gtex

 

Your request #29078: "Develop a multi-view knowledge-based neural network model to integrate heterogeneous genomics data and detect conserved mechanisms for cellular lifespan regulation" for access to NCBI dbGaP Program datasets has been authorized by your institutional Signing Official (Meredith Perry) and forwarded to the responsible Data Access Committee(s) (DAC) for review.

The result of DAC review will be communicated by email. If access is approved, that communication also will contain instructions for access to the datasets.

The DAC(s) responsible for reviewing your request can be contacted by email to

Thursday, June 3, 2021

student research work hours at UTC

 during semester, 20 hours maximal

during summer, 30 hours maximal, more than this need to be classified as full-time employee. 

Wednesday, June 2, 2021

graph neural nework


 

UTC PhD require 72 credit hours

 

UTC PhD course Requirements:

Doctoral students must complete a minimum of 72 hours beyond the bachelor’s degree, exclusive of credit for the master’s thesis. These hours must include a minimum of 24 semester hours in Doctoral Research and Dissertation and a minimum of 48 semester hours in other courses. At least 12 of the required 24 research and dissertation hours must be in Dissertation from an established concentration area.







UTC faculty website

 

I wanted to provide you with an update concerning your faculty web profile (http://www.utc.edu/faculty/hong-qin/). Communication and Marketing were able to migrate your content over to the following pages:

Events:  https://blog.utc.edu/hong-qin/events/

ICompBio: https://blog.utc.edu/hong-qin/icompbio/

CyberCorps: https://blog.utc.edu/hong-qin/cybercorps/

 

I went ahead and hyperlinked these pages for you on your faculty web profile (http://www.utc.edu/faculty/hong-qin/), which will update in the next few hours to display the links. Edits in Digital Measures are pushed to your webpage on a 12-hour cycle. By the time you get this email, the changes may be reflected. If you wish to edit the list of links on your faculty web profile, you can do so by logging into digital measures and clicking on “Biography.” (Guide here: https://utc.teamdynamix.com/TDClient/2717/Portal/KB/ArticleDet?ID=131677#Topic3)

 

To edit any of the pages on the blog (such as https://blog.utc.edu/hong-qin/cybercorps/) you can do so by going to https://blog.utc.edu/ and clicking “Log In” at the bottom of the page. Here is a direct link to the blog log-in page: https://blog.utc.edu/wp-login.php. 

 


 

Hebbian, Oja learning

 14:16:01 From Hong Qin to Everyone:

https://en.wikipedia.org/wiki/Lasso_(statistics)

14:24:48 From Trevor Peyton to Everyone:

https://en.wikipedia.org/wiki/Hebbian_theory

14:25:25 From Trevor Peyton to Everyone:

https://en.wikipedia.org/wiki/Generalized_Hebbian_algorithm

14:26:08 From Trevor Peyton to Everyone:

https://en.wikipedia.org/wiki/Oja%27s_rule