I study computational and quantitative biology with a focus on network aging. This site is to serve as my note-book and to effectively communicate with my students and collaborators. Every now and then, a blog may be of interests to other researchers or teachers. Views in this blog are my own. All rights of research results and findings on this blog are reserved. See also http://youtube.com/c/hongqin
Tuesday, January 21, 2014
BIO125, Jan 21, 2014, MSH2, serial dilution with graphing paper and playdough
1.5 hours spent on going over reading assignments, the abstract of Gammie Genetic 2007.
I used beads again to explain microsatellite and replication errors.
I spent about 40 minutes on sequence alignment, conservation to explain 'cognant' sites.
I use different models of cars to explain that 'wheels' and 'driver seat' are conserved, but the 'back seat' are not.
>1hour on serial dilution with graphing paper and playdough. 10X, 1X, 0.1X
Some students have trouble to understand 10X and 1X and how are connection to absolute concentrations.
C1V1 = C2V2
When applying the mass conservation formula, some students have trouble to decide which volume should the unknown.
Annoucement: read protocol 3.3, mathbench assignment 3.1 for quiz on Thursday.