Tuesday, July 8, 2014

Wuttke et al 2012 PlosGenetic gene network of Dietary Restriction


http://genomics.senescence.info/diet/


Wuttke12 concluded "DR commonly suppress translation" and "stimulating an ancient reproduction-related process".

Ad libitum vs DR.

Why spermidine?



Wuttke12 argues that DR extends lifespan by 'rejuvenation' by activating meiosis-related genes. This argument cannot explain how DR works in E. coli or prokaryotic cells.





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