Friday, November 21, 2014

MCL algorithm comparison

Brohee and van Helden 2006, BMC [BH06]
BH06 compared Markov Clustering (MCL), Restricted Neighborhood Search Clustering (RNSC), Super Paramagnetic Clustering (SPC), and Molecular Complex Detection (MCODE), using annotated protein complex as bench mark. Random noises were introduced by randomly adding and deleting edges. MCL is the most reliable and robust method. 


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