Tuesday, January 3, 2017

cancer reading notes

Driver and passenger mutations

Solid tumors have 33-66 somatic nonsynonymous mutations.
140 such genes on cell fate, cell survival and genome maintenance
Heterogeneity in tumor cells


KEGG A collection of manually curated pathway models
www.genome.jp/kegg/pathway.html
BIOCARTA A collection of pathways for more than 300 species
http://www.biocarta.com
PID A collection of curated pathways for human signaling and regulatory processes
http://pid.nci.nih.gov/

Pathguide A meta- database providing an overview of all web-accessible biological pathway and network databases
http://www.pathguide.org/
REACTOME A resource of curated human pathways http://www.reactome.org/

MSidDB A collection of diseased-related gene sets
http://www.broadinstitute.org/gsea/msigdb/collections.jsp

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