I study computational and quantitative biology with a focus on network aging. This site is to serve as my note-book and to effectively communicate with my students and collaborators. Every now and then, a blog may be of interests to other researchers or teachers. Views in this blog are my own. All rights of research results and findings on this blog are reserved. See also http://youtube.com/c/hongqin
Sunday, January 1, 2017
control coefficient and metabolic control
control coefficient, which is similar to sensitivity analysis and defines relative changes of a system (e.g. fluxes or concentrations) in response to a perturbation.
See Kacser & Burns 1973, Heinrich & Rapoport 1974, Burns et al. 1985
Kacser, H. & Burns, J.A. (1973) The control of flux. Symp. Soc. Exp. Biol. 27, 65-104.
Heinrich, R. & Rapoport, T.A. (1974) A linear steady-state treatment of enzymatic chains. General properties, control and effector strength., Eur. J. Biochem. 42, 89-95.
Burns, J.A., Cornish-Bowden, A., Groen, A.K., Heinrich, R., Kacser, H., Porteous, J.W., Rapoport, S.M., Rapoport T.A., Stucki, J.W., Tager, J.M., Wanders, R.J.A. & Westerhoff, H.V. (1985), Control of metabolic systems. Trends Biochem. Sci. 10, 16.