Tuesday, June 4, 2013

Notes, Vaupel, Manton, Stallard 1979, failty model

Reading notes on Vaupel, Manton, Stallard 1979, Demography, The impact of heterogeneity in individual frailty on the dynamics of mortality.

This is really a classic paper to study the effect of heterogeneity on aging.


VMS79 defined frailty $z$ as $\mu(z) = z \mu$, where $mu$ is the mortality rate (termed force of mortality in the paper).

VMS79 used a gamma distribution to model frailty. They found that frailty among the survivors at age $x$ is gamma distributed with the same shape parameter $k$ at birth. The second parameter is
$\lamda(x) = \lambda + H(x)$.




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