Sunday, March 9, 2014

yeast MSH2 gene expression peaks in G1 phase (protein peak in S phase?)

MSH2 Expression and yeast cell cycle

The yeast MSH2 mRNA peak in G1 phase.  If the MSH2 protein have half-live longer than G1 phase, the protein MSH2 level can be high in both G1 and S phases.


From:
http://genome-www.stanford.edu/cgi-bin/cellcycle/drawCCquery.pl

The original paper, Cho 1998








cell cycle and gene expression:
http://www.nature.com/nrm/journal/v2/n11/box/nrm1101-815a_BX1.html




At GEO, GSE3635, two cell cycle data of wildtype W303
The GEO Dataset Browser allow user to look at gene name and its expression profile.  I did not find a way to generate a heatmap?!




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